California Association
for
Medical Laboratory Technology

Distance Learning Program

 

Hemoglobin A1c Testing of Patients with Hemoglobinopathies

by
Amy Fang
Graduate Student in Clinical Science
California State University, Dominguez Hills

Ellen Hope Kearns, Ph.D.
Professor, College of Health & Human Services
California State University, Dominguez Hills

Helen M. Sowers, M.A., CLS
Dept of Biological Science (retired)
California State University, East Bay

Course Number: DL-973
1.0 CE/Contact Hour
Level of Difficulty: Intermediate

© California Association for Medical Laboratory Technology.
Permission to reprint any part of these materials, other than for credit from CAMLT, must be obtained in writing from the CAMLT Executive Office.

CAMLT is approved by the California Department of Health Services as a
CA CLS Accrediting Agency (#0021)
and this course is is approved by ASCLS for the P.A.C.E.¨ Program (#519)

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Fremont, CA 94538-1766
Phone: 510-792-4441
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Notification of Distance Learning Deadline
All continuing education units required to renew your license must be earned no later than the expiration date printed on your license. If some of your units are made up of Distance Learning courses, please allow yourself enough time to retake the test in the event you do not pass on the first attempt. CAMLT urges you to earn your CE units early!. 

This course is configured to be completed on-line. You can register for the course, submit secure payment using a credit card via PayPal, take the quiz on-line and receive your graded score.   If you pass, your certificate will be mailed to you from the CAMLT office.

If you fail, you must submit new payment and obtain a new PayPal receipt each time you take the test.   A certificate will be issued only if you have paid for re-taking the course and you pass the test.

If you want to submit your registration and quiz via fax or mail you should print the Adobe Acrobat version of the course which includes the required Registration/Quiz form.
Links to:
On-line REGISTRATION, PAYMENT and QUIZ
Printable Acrobat version of this course *
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Hemoglobin A1c Testing of Patients with Hemoglobinopathies

Completion of this course requires downloading the Acrobat Version (link above).
You may then print a copy or view the downloaded file on your computer to see the course material.
Only the Introduction and Objectives appear below.

INTRODUCTION
Hemoglobin A1c is the most useful single index of blood glucose control available to diabetics. Increased HbA1c is closely linked to risk of long-term microvascular diabetic complications (1). HbA1c is measured in the laboratory using a variety of methods. The presence of hemoglobinopathies in a patient presents a confounder to HbA1c testing, yielding erroneous laboratory test results. Beginning with a description of HbA1c and its relationship to blood glucose followed by methods of testing for HbA1c in the laboratory, this course focuses on the problematic aspects of testing for HbA1c in a patient with a hemoglobinopathy using each of these methods. General conclusions, limitations, and recommendations for testing are given.

OBJECTIVES:
On completion of this course the participant will be able to:

    1. describe hemoglobin A1 structure and function
    2. discuss the formation of hemoglobin A1c (HbA1c) and its relationship to blood glucose levels
    3. give the normal HbA1c range and the recommended percentage for diabetics
    4. outline the chronic complications of diabetes due to long term increase in blood glucose
    5. list the names of three HbA1c testing methodologies
    6. state examples for each of the HbA1c methodologies
    7. describe how hemoglobinopathies may give erroneous results in HbA1c testing

Link to On-line REGISTRATION, PAYMENT and QUIZ to submit for credit